MANFRA, MICHELE
 Distribuzione geografica
Continente #
NA - Nord America 6.761
AS - Asia 2.610
EU - Europa 1.842
SA - Sud America 180
AF - Africa 26
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 3
Totale 11.436
Nazione #
US - Stati Uniti d'America 6.610
CN - Cina 1.232
SG - Singapore 541
UA - Ucraina 518
VN - Vietnam 461
IT - Italia 421
HK - Hong Kong 220
DE - Germania 192
BR - Brasile 138
CA - Canada 129
GB - Regno Unito 121
SE - Svezia 117
FI - Finlandia 111
RU - Federazione Russa 95
FR - Francia 62
AT - Austria 39
IE - Irlanda 36
IN - India 32
NL - Olanda 30
PL - Polonia 28
BE - Belgio 26
TR - Turchia 25
JP - Giappone 23
AR - Argentina 17
ES - Italia 15
MX - Messico 15
ZA - Sudafrica 13
AU - Australia 12
CZ - Repubblica Ceca 10
ID - Indonesia 10
BD - Bangladesh 9
KR - Corea 9
PH - Filippine 8
IQ - Iraq 6
LT - Lituania 6
AE - Emirati Arabi Uniti 5
IR - Iran 5
PE - Perù 5
TW - Taiwan 5
EC - Ecuador 4
PT - Portogallo 4
PY - Paraguay 4
RO - Romania 4
CL - Cile 3
CO - Colombia 3
EG - Egitto 3
IL - Israele 3
PK - Pakistan 3
DO - Repubblica Dominicana 2
DZ - Algeria 2
ET - Etiopia 2
EU - Europa 2
NZ - Nuova Zelanda 2
OM - Oman 2
PS - Palestinian Territory 2
VE - Venezuela 2
AM - Armenia 1
BO - Bolivia 1
CH - Svizzera 1
EE - Estonia 1
FK - Isole Falkland (Malvinas) 1
GP - Guadalupe 1
GY - Guiana 1
HN - Honduras 1
HR - Croazia 1
HU - Ungheria 1
JO - Giordania 1
KE - Kenya 1
KZ - Kazakistan 1
LB - Libano 1
MA - Marocco 1
MD - Moldavia 1
MY - Malesia 1
MZ - Mozambico 1
NA - Namibia 1
NI - Nicaragua 1
NP - Nepal 1
RS - Serbia 1
SD - Sudan 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
SV - El Salvador 1
TH - Thailandia 1
TJ - Tagikistan 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
UZ - Uzbekistan 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 11.436
Città #
Woodbridge 677
Ann Arbor 669
Fairfield 642
Beijing 617
Houston 554
Ashburn 538
Jacksonville 446
Dong Ket 400
Chandler 295
Seattle 277
Wilmington 233
Hong Kong 213
Cambridge 198
The Dalles 184
Nanjing 178
Dallas 175
Singapore 170
Boardman 158
Kent 101
Toronto 101
New York 81
Princeton 77
Nanchang 72
Ogden 68
Los Angeles 65
Munich 55
Centro 48
Milan 48
Helsinki 39
Buffalo 37
Kunming 37
Dublin 36
Shenyang 35
London 30
Santa Clara 29
Moscow 27
Brussels 25
Tianjin 25
San Francisco 24
Vienna 24
Hebei 20
Ho Chi Minh City 20
São Paulo 20
Warsaw 20
Chicago 19
Napoli 19
Jiaxing 18
San Diego 18
Changsha 17
Guangzhou 16
Hangzhou 16
Dearborn 15
Verona 15
Nuremberg 14
Atlanta 12
Brooklyn 12
Council Bluffs 12
Falls Church 12
Jinan 12
Montreal 12
Tokyo 12
Amsterdam 11
Hanoi 11
Naples 11
Shanghai 11
Washington 11
Denver 10
Des Moines 10
Poplar 10
Turku 10
Xi'an 10
Boston 9
Chennai 9
Johannesburg 9
Lanzhou 9
Salerno 9
Brno 8
Columbus 8
Rome 8
Florence 7
Mumbai 7
Stockholm 7
Bari 6
Fisciano 6
Frankfurt am Main 6
Konak 6
Manchester 6
Mexico City 6
Norwalk 6
Palermo 6
Portland 6
Querétaro 6
San Jose 6
Cassano Allo Ionio 5
Duncan 5
Hounslow 5
Indiana 5
Lima 5
Osaka 5
Phoenix 5
Totale 8.335
Nome #
An 1H NMR study of the cytarabine degradation in clinical conditions to avoid drug waste, decrease therapy costs and improve patient compliance in acute leukemia 249
Anthocyanin composition and extractability in berry skin and wine of Vitis vinifera L. cv. Aglianico 239
Berry morphology and composition in irrigated and non-irrigated grapevine (Vitis vinifera L.) 232
Antitumor Agents. 3. Design, Synthesis, and Biological Evaluation of New Pyridoisoquinolindione and Dihydrothienoquinolindione Derivatives with Potent Cytotoxic Activity 215
Antitumor Agents. 1. Synthesis, Biological Evaluation, and Molecular Modeling of 5H-Pyrido[3,2-a]phenoxazin-5-one, a Compound with Potent Antiproliferative Activity 210
Evaluation of anti-inflammatory activity and fast UHPLC–DAD–IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano) 210
Nutraceutical value and toxicological profile of selected red wines from Morocco 208
An NMR Study of the Bortezomib Degradation under Clinical Use Conditions 196
Analisi quali-quantitativa di antociani in uve Aglianico sottoposte a due diversi regimi irrigui 194
Anti-inflammatory and antioxidant activity of polyphenolic extracts from Lactuca sativa (var.Maravilla de Verano) under different farming methods 193
Antitumor Agents. 2. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Substituted 5H-Pyridophenoxazin-5-ones with Potent Antiproliferative Activity 192
Antitumor Agents 6. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Spiro[imidazolidine-4,3′-thieno[2,3-g]quinoline]-tetraones and Spiro[thieno[2,3-g]quinoline-3,5′- [1,2,4]triazinane]-tetraones with Potent Antiproliferative Activity† 190
Nutraceutical properties and polyphenolic profile of berry skin and wine of Vitis vinifera L. (cv. Aglianico) 190
Different agronomic and fertilization systems affect polyphenolic profile, antioxidant capacity and mineral composition of lettuce 189
Trichoderma harzianum strain T-22 induces changes in phytohormone levels in cherry rootstocks (Prunus cerasus x P. canescens) 188
Anti-inflammatory potential and fast UHPLC-DAD-IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano) 178
Mechanochemistry of ibuprofen pharmaceutical 163
Bioavailable Citrus sinensis Extract: Polyphenolic Composition and Biological Activity 161
Polyphenolic pattern and in vitro cardioprotective properties of typical red wines from vineyards cultivated in Scafati (Salerno, Italy) 159
Antitumor Agents. 5. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Dimethyl-5H-pyridophenoxazin-5-ones, Tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-Benzopyridophenoxazin-5-ones with Potent Antiproliferative Activity 157
Anticancer Agents for Treatment of Acute and Chronic Myeloid Leukemia. Inhibitors of Protein Prenylation (Start Cup Federico II). 157
Yield parameters and antioxidant compounds of tomato fruits: the role of plant defense inducers with or without Cucumber mosaic virus infection 154
Rapid Screening of Antioxidant Anthocyanins in Autochthonous Nero d’Avola Grape Clones by Pre-column DPPH Reaction Coupled to UHPLC-UV/Vis-IT-TOF: a Strategy to Combine Chemical data and Genetic Diversity 153
Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone “Lempso” Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages 151
Dihydrithieno[2,3-b]naphto-4,9-dione analogues as anticancer agents: Synthesis and in cell pharmacological studies 146
Anti-inflammatory properties of polyphenolic extract from green lettuce (Lactuca sativa L.; var. Maravilla de Verano) and fast analytical characterization 146
Peptidome profiles and bioactivity elucidation of buffalo-milk dairy products after gastrointestinal digestion 146
Thiazolidin-4-one formation. Mechanistic and synthetic aspects of the reaction of imines and mercaptoacetic acid under microwave and conventional heating 145
Detailed polyphenolic profiling of Annurca apple (M. pumila Miller cv Annurca) by a combination of RP-UHPLC and HILIC, both hyphenated to IT-TOF mass spectrometry 142
Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells 141
Different water and light regimes affect ionome composition in grapevine (Vitis vinifera L.) 140
Reaction between quinone and thiazolidine. A study on the formation mechanism of new antiproliferative quinolindiones 139
Flavonoid Composition of Tarocco (Citrus sinensis L. Osbeck) Clone “Lempso” and Fast Antioxidant Activity Screening by DPPH-UHPLC-PDA-IT-TOF 139
Influence of chitosan on the antioxidant status of tomato plants infected by cucumber mosaic virus 136
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 135
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from fragment Virtual Screening 135
AN HPLC AND 1H NMR STUDY OF THE CYTARABINE DEGRADATION IN CLINICAL CONDITIONS TO AVOID DRUG WASTE, DECREASE THERAPY COSTS AND IMPROVE PATIENT COMPLIANCE 134
Evaluation of two sub-2 _m stationary phases, core–shell and totally porous monodisperse, in the second dimension of on-line comprehensive two dimensional liquid chromatography, a case study: Separation of milk peptides after expiration date. 133
Susceptibility to denaturation of caseins in milk samples for improving protein conformational study and their identification. 133
A new class of synthetic quinonic compounds acting as antiproliferative agents 132
Microwave-Assisted Synthesis of Pyridophenoxazinones, a Class of Antiproliferative Compounds 131
Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new L-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIa inhibitors 131
Susceptibility to denaturation of caseins in milk samples for improving protein conformational study and their identification 127
Chemical profiling of bioactive constituents in hop cones and pellets extracts by online comprehensive two-dimensional liquid chromatography with tandem mass spectrometry and direct infusion Fourier transform ion cyclotron resonance mass spectrometry 124
Modification of lipid profile in commercial cow milk samples before and after their expiration date: Evaluation of storage crucial parameters and possible environmentally friendly disposal alternatives 121
Antioxidant profile and in vitro cardiac radical-scavenging vs pro-oxidant effects of commercial red grape juices (Vitisvinifera L. cv. Aglianico N.) 118
Ultra high performance liquid chromatography with ion-trap TOF-MS for the fast characterization of flavonoids in Citrus bergamia juice 116
Synthesis and pharmacological characterization of conformationally restricted retigabine analogues as novel neuronal Kv7 channels activators 116
Effect of different soil fertilization treatments on phytochemicals, a case study: antioxidant polyphenols from Lactuca sativa (var. Maravilla de Verano) extract 113
Bioaccesibility and antinflammatory properties of Citrus Aurantii juice flavonoids 112
UHPLC profiling and effects on LPS-stimulated J774A.1 macrophages of flavonoide from bergamot (Citrus bergamia) juice, an underestimed waste product with high anti-inflammatory potential 110
Antioxidant profile and in vitro cardiac radical scavengings us pro-oxidant effects of commercial red grape juices (Vitisvinifera I.cv Aglianico) 109
Antioxidant profile and in vitro and cardioprotective properties of typical red and white wines from vineyards cultivated in Scafati (Salerno, Italy) 108
Anti-inflammatory activity of polyphenolic extracts from Lactuca sativa (var. Maravilla de Verano) under differentfertilizationsystems 107
Online comprehensive hydrophilic interaction chromatography ×reversed phase liquid chromatography coupled to mass spectrometryfor in depth peptidomic profile of microalgae gastro-intestinal digests 106
Comprehensive two dimensional liquid chromatography (LC × UHPLC): a powerful analytical tool for high resolution profiling of milk peptides after expiration date. 104
POLYPHENOLIC PROFILE IN BERRY SKIN AND WINE OF VITIS VINIFERA L. CV. AGLIANICO (BASILICATA, ITALY) 104
Synthesis and antiviral activity of quinolone and oxazine derivatives 104
New Antiviral INSTIs: Design, Synthesis and Biological Evaluation 103
Detailed peptide profiling of “Scotta”: from a dairy waste to a source of potential health-promoting compound 102
SAVING MONEY AND COMFORT BY GAINING CYTOSINE ARABINOSIDE MICROGRAMS 101
Bergamot essential oil extraction 99
Transition Metals Revert the Quinolinquinone Reactivity. 97
Microwave Assisted Synthesis of Pyridophenoxazinones, a class of Powerful Antiproliferative Compounds 94
I Piridofenossazinoni: una nuova classe di potenti composti antiproliferativi che si intercalano al DNA 93
Pursuing the Development of New Antiviral Entry Inhibitors 91
Synthesis, Antiproliferative Activity, and Molecular Modelling of New DNA Intercalating Pyridophenoxazinone Carboxamides 89
Citrus sinensis and Vitis vinifera Protect Cardiomyocytes from Doxorubicin-Induced Oxidative Stress: Evaluation of Onconutraceutical Potential of Vegetable Smoothies 88
Organoleptic evaluation of lemon liqueurs deriving from biological agriculture 82
. Evaluation of the antioxidant and antiproliferative potential properties of phytocomplexes extracted from Mediterranean area fruits 81
DESIGN AND PRECLINICAL DEVELOMENT OF CP86, A NEW POTENT IN VIVO ANTIEPILEPTIC AGENT 81
Ishtar Phytotherapeutic Products (Start Cup Campania 2010) 80
QUALI-QUANTITATIVE PROFILING OF ANTHOCYANINS OF SICILIAN GRAPES THROUGH UHPLC-DAD-ESI-IT-TOF 77
Pursuing the Development of New Antiviral INSTIs 75
Hypolipidemic activity and in depth analytical investigation of bergamot juice flavonoids: from a waste product to a potential nutraceutical 72
Inibitori delle topoisomerasi: derivati chinolin-chinonici con attività antiproliferativa 70
14th International Conference on the Chemistry of Selenium and Tellurium ICCST-14 (3rd-7th June 2019) 69
Novel Anticancer Drug 5H-pyro[3,2-a] Phenoxazin-5-one (PPH) Regulates lncRNA HOTAIR and HOXC genes in Human MCF-7 Cells 68
Sintesi di nuovi agenti anticancro contenenti sistemi chinolinonici, isochinolinonici e fenossazinonici” 66
Potential Role of Natural Antioxidant Products in Oncological Diseases 65
13th Young Medicinal Chemist's Symposium (13NPCF). 61
Dipropyleneglycol Dimethylether, New Green Solvent for Solid-Phase Peptide Synthesis: Further Challenges to Improve Sustainability in the Development of Therapeutic Peptides 53
13th Young Medicinal Chemist's Symposium (13NPCF). 52
13th Young Medicinal Chemist's Symposium (13NPCF). 51
The Ion Channels Involved in Oxidative Stress-Related Gastrointestinal Diseases 50
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 50
N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach 50
La Chimica guida lo sviluppo sostenibile 48
XXVI National Meeting in Medicinal Chemistry -XII Young Medicinal Chemists’ Symposium 46
Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress 45
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors 45
Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential 44
Stereoselective Synthesis of Selenium-Containing Glycoconjugates via the Mitsunobu Reaction 42
International Conference on New Trends in Chemistr (ICNTC-2020). 41
Advancing profiling of secondary antioxidant metabolites in Allium cepa PDO leaf extract: Online comprehensive two-dimensional liquid chromatography with high-resolution mass spectrometry and pre-column DPPH assay 36
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization 32
XXVI National Meeting in Medicinal Chemistry 31
XXXVI National Meeting in Medicinal Chemistry 30
Chemistry meets Industry and Society A creative showcase conference 29
XXVI National Meeting in Medicinal Chemistry 28
Totale 11.518
Categoria #
all - tutte 52.882
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 52.882


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.076 0 0 0 0 0 135 88 99 37 149 138 430
2021/2022684 54 89 100 45 30 43 31 42 48 17 29 156
2022/2023750 125 24 20 83 82 94 1 71 151 33 43 23
2023/2024607 43 36 47 16 76 94 5 31 123 11 36 89
2024/20251.511 73 20 218 39 81 51 175 125 285 74 179 191
2025/20261.647 216 178 179 390 529 155 0 0 0 0 0 0
Totale 11.666