MANFRA, MICHELE
 Distribuzione geografica
Continente #
NA - Nord America 8.456
AS - Asia 3.045
EU - Europa 2.322
SA - Sud America 206
AF - Africa 45
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 3
Totale 14.092
Nazione #
US - Stati Uniti d'America 8.265
CN - Cina 1.327
SG - Singapore 622
IT - Italia 548
UA - Ucraina 519
VN - Vietnam 513
HK - Hong Kong 255
RU - Federazione Russa 249
DE - Germania 205
FR - Francia 163
BR - Brasile 157
FI - Finlandia 152
CA - Canada 151
GB - Regno Unito 133
SE - Svezia 117
BD - Bangladesh 104
IN - India 55
NL - Olanda 40
AT - Austria 39
IE - Irlanda 38
PL - Polonia 36
TR - Turchia 28
BE - Belgio 27
JP - Giappone 27
MX - Messico 22
AR - Argentina 21
IQ - Iraq 18
ZA - Sudafrica 18
ES - Italia 16
PK - Pakistan 14
AU - Australia 13
AE - Emirati Arabi Uniti 11
ID - Indonesia 11
CZ - Repubblica Ceca 10
KR - Corea 10
PH - Filippine 9
LT - Lituania 7
TW - Taiwan 7
EC - Ecuador 5
ET - Etiopia 5
IR - Iran 5
KE - Kenya 5
PE - Perù 5
PT - Portogallo 5
CO - Colombia 4
DZ - Algeria 4
HN - Honduras 4
HU - Ungheria 4
PY - Paraguay 4
RO - Romania 4
SV - El Salvador 4
CL - Cile 3
EG - Egitto 3
IL - Israele 3
MA - Marocco 3
MY - Malesia 3
PS - Palestinian Territory 3
VE - Venezuela 3
CH - Svizzera 2
DO - Repubblica Dominicana 2
EU - Europa 2
JM - Giamaica 2
JO - Giordania 2
NP - Nepal 2
NZ - Nuova Zelanda 2
OM - Oman 2
SN - Senegal 2
TH - Thailandia 2
UZ - Uzbekistan 2
AM - Armenia 1
AO - Angola 1
BH - Bahrain 1
BO - Bolivia 1
BS - Bahamas 1
EE - Estonia 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
GP - Guadalupe 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
KW - Kuwait 1
KZ - Kazakistan 1
LB - Libano 1
LV - Lettonia 1
MD - Moldavia 1
MZ - Mozambico 1
NA - Namibia 1
NI - Nicaragua 1
NO - Norvegia 1
PR - Porto Rico 1
QA - Qatar 1
RS - Serbia 1
SA - Arabia Saudita 1
SD - Sudan 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
TJ - Tagikistan 1
TN - Tunisia 1
Totale 14.089
Città #
Ashburn 767
Woodbridge 677
Ann Arbor 669
Fairfield 642
Beijing 637
Houston 561
San Jose 560
Council Bluffs 503
Jacksonville 447
Dong Ket 400
Chandler 295
Seattle 278
Hong Kong 247
Wilmington 234
Singapore 205
Cambridge 198
Dallas 184
The Dalles 184
Nanjing 179
Boardman 159
Toronto 106
New York 104
Kent 101
Lauterbourg 95
Moscow 81
Helsinki 80
Princeton 77
Los Angeles 76
Nanchang 72
Ogden 68
Milan 58
Munich 55
Santa Clara 49
Centro 48
Buffalo 45
Chicago 38
Dublin 37
Ho Chi Minh City 37
Kunming 37
Shenyang 35
London 32
Warsaw 26
Brussels 25
Hanoi 25
San Francisco 25
Tianjin 25
Vienna 24
São Paulo 22
Rome 21
Atlanta 20
Hebei 20
Naples 20
Napoli 19
Orem 19
San Diego 19
Changsha 18
Jiaxing 18
Guangzhou 17
Hangzhou 17
Nuremberg 16
Shanghai 16
Tokyo 16
Amsterdam 15
Dearborn 15
Verona 15
Chennai 14
Montreal 14
Brooklyn 12
Denver 12
Des Moines 12
Falls Church 12
Frankfurt am Main 12
Jinan 12
Boston 11
Johannesburg 11
Poplar 11
Washington 11
Fisciano 10
Mumbai 10
Turku 10
Xi'an 10
Columbus 9
Lanzhou 9
Salerno 9
Bari 8
Brno 8
Mexico City 8
Palermo 8
Querétaro 8
Rio de Janeiro 8
Düsseldorf 7
Florence 7
Manchester 7
Phoenix 7
Potenza 7
Stockholm 7
Konak 6
Norwalk 6
Portland 6
Ankara 5
Totale 10.154
Nome #
An 1H NMR study of the cytarabine degradation in clinical conditions to avoid drug waste, decrease therapy costs and improve patient compliance in acute leukemia 296
Anthocyanin composition and extractability in berry skin and wine of Vitis vinifera L. cv. Aglianico 288
Berry morphology and composition in irrigated and non-irrigated grapevine (Vitis vinifera L.) 283
Nutraceutical value and toxicological profile of selected red wines from Morocco 238
Antitumor Agents. 3. Design, Synthesis, and Biological Evaluation of New Pyridoisoquinolindione and Dihydrothienoquinolindione Derivatives with Potent Cytotoxic Activity 235
Trichoderma harzianum strain T-22 induces changes in phytohormone levels in cherry rootstocks (Prunus cerasus x P. canescens) 233
Antitumor Agents 6. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Spiro[imidazolidine-4,3′-thieno[2,3-g]quinoline]-tetraones and Spiro[thieno[2,3-g]quinoline-3,5′- [1,2,4]triazinane]-tetraones with Potent Antiproliferative Activity† 230
Antitumor Agents. 1. Synthesis, Biological Evaluation, and Molecular Modeling of 5H-Pyrido[3,2-a]phenoxazin-5-one, a Compound with Potent Antiproliferative Activity 230
An NMR Study of the Bortezomib Degradation under Clinical Use Conditions 229
Evaluation of anti-inflammatory activity and fast UHPLC–DAD–IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano) 227
Antitumor Agents. 2. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Substituted 5H-Pyridophenoxazin-5-ones with Potent Antiproliferative Activity 218
Analisi quali-quantitativa di antociani in uve Aglianico sottoposte a due diversi regimi irrigui 216
Anti-inflammatory and antioxidant activity of polyphenolic extracts from Lactuca sativa (var.Maravilla de Verano) under different farming methods 210
Different agronomic and fertilization systems affect polyphenolic profile, antioxidant capacity and mineral composition of lettuce 207
Nutraceutical properties and polyphenolic profile of berry skin and wine of Vitis vinifera L. (cv. Aglianico) 202
Anti-inflammatory potential and fast UHPLC-DAD-IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano) 202
Bioavailable Citrus sinensis Extract: Polyphenolic Composition and Biological Activity 186
Anticancer Agents for Treatment of Acute and Chronic Myeloid Leukemia. Inhibitors of Protein Prenylation (Start Cup Federico II). 181
Peptidome profiles and bioactivity elucidation of buffalo-milk dairy products after gastrointestinal digestion 180
Mechanochemistry of ibuprofen pharmaceutical 179
Antitumor Agents. 5. Synthesis, Structure-Activity Relationships, and Biological Evaluation of Dimethyl-5H-pyridophenoxazin-5-ones, Tetrahydro-5H-benzopyridophenoxazin-5-ones, and 5H-Benzopyridophenoxazin-5-ones with Potent Antiproliferative Activity 176
Yield parameters and antioxidant compounds of tomato fruits: the role of plant defense inducers with or without Cucumber mosaic virus infection 176
Polyphenolic pattern and in vitro cardioprotective properties of typical red wines from vineyards cultivated in Scafati (Salerno, Italy) 173
Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone “Lempso” Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages 173
Rapid Screening of Antioxidant Anthocyanins in Autochthonous Nero d’Avola Grape Clones by Pre-column DPPH Reaction Coupled to UHPLC-UV/Vis-IT-TOF: a Strategy to Combine Chemical data and Genetic Diversity 169
Thiazolidin-4-one formation. Mechanistic and synthetic aspects of the reaction of imines and mercaptoacetic acid under microwave and conventional heating 168
AN HPLC AND 1H NMR STUDY OF THE CYTARABINE DEGRADATION IN CLINICAL CONDITIONS TO AVOID DRUG WASTE, DECREASE THERAPY COSTS AND IMPROVE PATIENT COMPLIANCE 168
Different water and light regimes affect ionome composition in grapevine (Vitis vinifera L.) 167
Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells 165
Anti-inflammatory properties of polyphenolic extract from green lettuce (Lactuca sativa L.; var. Maravilla de Verano) and fast analytical characterization 164
Influence of chitosan on the antioxidant status of tomato plants infected by cucumber mosaic virus 163
Dihydrithieno[2,3-b]naphto-4,9-dione analogues as anticancer agents: Synthesis and in cell pharmacological studies 162
Reaction between quinone and thiazolidine. A study on the formation mechanism of new antiproliferative quinolindiones 161
Flavonoid Composition of Tarocco (Citrus sinensis L. Osbeck) Clone “Lempso” and Fast Antioxidant Activity Screening by DPPH-UHPLC-PDA-IT-TOF 159
A new class of synthetic quinonic compounds acting as antiproliferative agents 157
Detailed polyphenolic profiling of Annurca apple (M. pumila Miller cv Annurca) by a combination of RP-UHPLC and HILIC, both hyphenated to IT-TOF mass spectrometry 154
Antitumor agents 7. Synthesis, antiproliferative activity and molecular modeling of new L-lysine-conjugated pyridophenoxazinones as potent DNA-binding ligands and topoisomerase IIa inhibitors 152
Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from fragment Virtual Screening 152
Susceptibility to denaturation of caseins in milk samples for improving protein conformational study and their identification. 150
Development and identification of a novel anti-HIV-1 peptide derived by modification of the N-terminal domain of HIV-1 integrase 150
Evaluation of two sub-2 _m stationary phases, core–shell and totally porous monodisperse, in the second dimension of on-line comprehensive two dimensional liquid chromatography, a case study: Separation of milk peptides after expiration date. 149
Microwave-Assisted Synthesis of Pyridophenoxazinones, a Class of Antiproliferative Compounds 147
Susceptibility to denaturation of caseins in milk samples for improving protein conformational study and their identification 144
Modification of lipid profile in commercial cow milk samples before and after their expiration date: Evaluation of storage crucial parameters and possible environmentally friendly disposal alternatives 142
New Antiviral INSTIs: Design, Synthesis and Biological Evaluation 141
Chemical profiling of bioactive constituents in hop cones and pellets extracts by online comprehensive two-dimensional liquid chromatography with tandem mass spectrometry and direct infusion Fourier transform ion cyclotron resonance mass spectrometry 141
Antioxidant profile and in vitro cardiac radical scavengings us pro-oxidant effects of commercial red grape juices (Vitisvinifera I.cv Aglianico) 139
Synthesis and pharmacological characterization of conformationally restricted retigabine analogues as novel neuronal Kv7 channels activators 139
Antioxidant profile and in vitro cardiac radical-scavenging vs pro-oxidant effects of commercial red grape juices (Vitisvinifera L. cv. Aglianico N.) 133
Ultra high performance liquid chromatography with ion-trap TOF-MS for the fast characterization of flavonoids in Citrus bergamia juice 132
Effect of different soil fertilization treatments on phytochemicals, a case study: antioxidant polyphenols from Lactuca sativa (var. Maravilla de Verano) extract 130
Anti-inflammatory activity of polyphenolic extracts from Lactuca sativa (var. Maravilla de Verano) under differentfertilizationsystems 130
Bioaccesibility and antinflammatory properties of Citrus Aurantii juice flavonoids 128
Novel Anticancer Drug 5H-pyro[3,2-a] Phenoxazin-5-one (PPH) Regulates lncRNA HOTAIR and HOXC genes in Human MCF-7 Cells 127
I Piridofenossazinoni: una nuova classe di potenti composti antiproliferativi che si intercalano al DNA 124
Online comprehensive hydrophilic interaction chromatography ×reversed phase liquid chromatography coupled to mass spectrometryfor in depth peptidomic profile of microalgae gastro-intestinal digests 123
Antioxidant profile and in vitro and cardioprotective properties of typical red and white wines from vineyards cultivated in Scafati (Salerno, Italy) 122
UHPLC profiling and effects on LPS-stimulated J774A.1 macrophages of flavonoide from bergamot (Citrus bergamia) juice, an underestimed waste product with high anti-inflammatory potential 122
. Evaluation of the antioxidant and antiproliferative potential properties of phytocomplexes extracted from Mediterranean area fruits 121
13th Young Medicinal Chemist's Symposium (13NPCF). 121
Comprehensive two dimensional liquid chromatography (LC × UHPLC): a powerful analytical tool for high resolution profiling of milk peptides after expiration date. 119
SAVING MONEY AND COMFORT BY GAINING CYTOSINE ARABINOSIDE MICROGRAMS 117
POLYPHENOLIC PROFILE IN BERRY SKIN AND WINE OF VITIS VINIFERA L. CV. AGLIANICO (BASILICATA, ITALY) 117
Detailed peptide profiling of “Scotta”: from a dairy waste to a source of potential health-promoting compound 117
Microwave Assisted Synthesis of Pyridophenoxazinones, a class of Powerful Antiproliferative Compounds 114
Synthesis and antiviral activity of quinolone and oxazine derivatives 113
Pursuing the Development of New Antiviral Entry Inhibitors 113
Bergamot essential oil extraction 111
DESIGN AND PRECLINICAL DEVELOMENT OF CP86, A NEW POTENT IN VIVO ANTIEPILEPTIC AGENT 110
Transition Metals Revert the Quinolinquinone Reactivity. 108
Citrus sinensis and Vitis vinifera Protect Cardiomyocytes from Doxorubicin-Induced Oxidative Stress: Evaluation of Onconutraceutical Potential of Vegetable Smoothies 106
Ishtar Phytotherapeutic Products (Start Cup Campania 2010) 105
Synthesis, Antiproliferative Activity, and Molecular Modelling of New DNA Intercalating Pyridophenoxazinone Carboxamides 101
Organoleptic evaluation of lemon liqueurs deriving from biological agriculture 96
Dipropyleneglycol Dimethylether, New Green Solvent for Solid-Phase Peptide Synthesis: Further Challenges to Improve Sustainability in the Development of Therapeutic Peptides 94
14th International Conference on the Chemistry of Selenium and Tellurium ICCST-14 (3rd-7th June 2019) 93
QUALI-QUANTITATIVE PROFILING OF ANTHOCYANINS OF SICILIAN GRAPES THROUGH UHPLC-DAD-ESI-IT-TOF 93
Potential Role of Natural Antioxidant Products in Oncological Diseases 92
Inibitori delle topoisomerasi: derivati chinolin-chinonici con attività antiproliferativa 86
Hypolipidemic activity and in depth analytical investigation of bergamot juice flavonoids: from a waste product to a potential nutraceutical 85
Pursuing the Development of New Antiviral INSTIs 83
13th Young Medicinal Chemist's Symposium (13NPCF). 81
13th Young Medicinal Chemist's Symposium (13NPCF). 80
Sintesi di nuovi agenti anticancro contenenti sistemi chinolinonici, isochinolinonici e fenossazinonici” 80
The Ion Channels Involved in Oxidative Stress-Related Gastrointestinal Diseases 79
Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress 79
Advancing profiling of secondary antioxidant metabolites in Allium cepa PDO leaf extract: Online comprehensive two-dimensional liquid chromatography with high-resolution mass spectrometry and pre-column DPPH assay 79
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors 75
N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach 74
XXVI National Meeting in Medicinal Chemistry -XII Young Medicinal Chemists’ Symposium 73
La Chimica guida lo sviluppo sostenibile 69
International Conference on New Trends in Chemistr (ICNTC-2020). 65
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity 64
An adamantylureido-benzylamide aniline as FLAP/sEH dual inhibitor: Rational design, in vitro and in vivo lipidomic profiling 64
Antitumor Mechanisms of Lycium barbarum Fruit: An Overview of In Vitro and In Vivo Potential 63
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition 60
Stereoselective Synthesis of Selenium-Containing Glycoconjugates via the Mitsunobu Reaction 60
New green base for Fmoc removal in solid-phase peptide synthesis: 1,5-diazabicyclo[4.3.0]non-5-ene (DBN), a promising sustainable alternative to piperidine 59
Exploring Endocannabinoid System: Unveiling New Roles in Modulating ER Stress 59
XXXVI National Meeting in Medicinal Chemistry 59
Totale 13.879
Categoria #
all - tutte 60.690
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.690


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021430 0 0 0 0 0 0 0 0 0 0 0 430
2021/2022684 54 89 100 45 30 43 31 42 48 17 29 156
2022/2023750 125 24 20 83 82 94 1 71 151 33 43 23
2023/2024607 43 36 47 16 76 94 5 31 123 11 36 89
2024/20251.511 73 20 218 39 81 51 175 125 285 74 179 191
2025/20264.306 216 178 179 390 529 414 618 171 313 558 587 153
Totale 14.325