Chronic myelogenous leukemia (CML) is one of the most common tumors. CML iscaused by a geneticalteration of the Philadelphia (Ph) chromosome, which forms the hybrid protein BCR/Abl1.Inhibiting BCR-ABL expression has long been the gold-standard approach in CML treatment. Trifolium repens (TR) , commonly known as white clover is used as a fodder crop for cattle, but to date,its potential anticancer activity has not been explored2. In this study, we investigated the antitumor action of TR in several cancer cell lines, focusing specifically on its effect in CML cells.
13th Young Medicinal Chemist's Symposium (13NPCF).
Manfra, M.;
2021-01-01
Abstract
Chronic myelogenous leukemia (CML) is one of the most common tumors. CML iscaused by a geneticalteration of the Philadelphia (Ph) chromosome, which forms the hybrid protein BCR/Abl1.Inhibiting BCR-ABL expression has long been the gold-standard approach in CML treatment. Trifolium repens (TR) , commonly known as white clover is used as a fodder crop for cattle, but to date,its potential anticancer activity has not been explored2. In this study, we investigated the antitumor action of TR in several cancer cell lines, focusing specifically on its effect in CML cells.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Trifolium13th Young Medicinal Chemist's Symposium (13NPCF)..pdf
accesso aperto
Licenza:
Dominio pubblico
Dimensione
1.71 MB
Formato
Adobe PDF
|
1.71 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
