14th International Conference on the Chemistry of Selenium and Tellurium ICCST-14 (3rd-7th June 2019)

Selenium is an essential trace element for human health owing many biological functions (Fig. 1). Indeed, Reactive Selenium Species (RSeS),3 like redox and biologically active selenium molecules of natural origin, have been gaining interest over the past decade and have led to the development of various reaction strategies for accessing new Se-compounds that turned out to be potent antioxidant agents with modest effect on normal tissues and clinically well tolerated.4 Among the other molecules with good antioxidant properties are polyphenolic compounds,5 as caffeic acid, curcumin and dopamine. As part of our current interest in novel and more efficient supplements to be used in oxidative stress prevention, we designed and synthetized new molecules having both a phenolic moiety and selenium in a sugar-type structure which in turn should provide a carrier function.