. Evaluation of the antioxidant and antiproliferative potential properties of phytocomplexes extracted from Mediterranean area fruits

Breast and cervical cancer represents the first and the second cause of death for women worldwide1,2. Therefore, new advanced chemotherapies applications are very urgently needed this cancer. High attention has been paid to natural compounds in fruits and vegetables with potential nutraceutical properties. In this regard, dietary polyphenols have been widely demonstrated to be able to not only reduce oxidative and inflammatory stress, but also decrease proliferation of cancer cells. However, the biological activity of various food plants has not yet been studied. This work aims to characterize the nutraceutical potential of four fruits such as, Malpighia emarginata (MEE), Arbutus unedo (AUE), Goji berries (LBE), Annona cherimola (ACE). For this reason, our study focused on the evaluation of antioxidant potential and antiproliferative activity of polyphenol extracts on cervical cancer (HeLa) and breast cancer (MCF-7) cell line.