Cytarabine, the 4-Amino-1-(β-D-arabinofuranosyl)-2(1H)-pyrimidinone, (ARA-C), is an antimetabolite cytidine analogue used worldwide as key drug in the management of leukaemia. As specified in the manufacturers’ instructions, once the components – sterile water and ARA-C powder – are unpackaged and mixed, the solution begins to degrade after 6 hours at room temperature and 12 hours at 4 °C
AN HPLC AND 1H NMR STUDY OF THE CYTARABINE DEGRADATION IN CLINICAL CONDITIONS TO AVOID DRUG WASTE, DECREASE THERAPY COSTS AND IMPROVE PATIENT COMPLIANCE
De Nisco, Mauro;MANFRA, MICHELE;
2016-01-01
Abstract
Cytarabine, the 4-Amino-1-(β-D-arabinofuranosyl)-2(1H)-pyrimidinone, (ARA-C), is an antimetabolite cytidine analogue used worldwide as key drug in the management of leukaemia. As specified in the manufacturers’ instructions, once the components – sterile water and ARA-C powder – are unpackaged and mixed, the solution begins to degrade after 6 hours at room temperature and 12 hours at 4 °CFile in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
2016) Asbtract Denmark.pdf
accesso aperto
Tipologia:
Documento in Post-print
Licenza:
Dominio pubblico
Dimensione
1.39 MB
Formato
Adobe PDF
|
1.39 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
