The inter-molecular carbolithiation of unfunctionalized and functionalized alkenes, followed by electrophile trapping, provides a versatile and useful tool for the construction of complex molecular systems, allowing the simultaneous creation of up to two novel carbon-carbon or carbon-heteroatom bonds. In this review a full overview oninter-molecular carbolithiation processes is reported, with a main focus on the chemo-, regio- and stereo-control of the reaction and on the strategies for asymmetric processes.

Regio- And stereoselective intermolecular carbolithiation reactions

Marsico G.;Scafato P.;Belviso S.;Superchi S.
2020-01-01

Abstract

The inter-molecular carbolithiation of unfunctionalized and functionalized alkenes, followed by electrophile trapping, provides a versatile and useful tool for the construction of complex molecular systems, allowing the simultaneous creation of up to two novel carbon-carbon or carbon-heteroatom bonds. In this review a full overview oninter-molecular carbolithiation processes is reported, with a main focus on the chemo-, regio- and stereo-control of the reaction and on the strategies for asymmetric processes.
2020
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11563/144514
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