Liposome insertion of a newly synthesized octa-carboranylhexylthio-porphyrazine (H2HECASPz) with potentiality in anticancer multiple therapy was described at molecular and supramolecular level. Host−guest interactions between H2HECASPz and the liposome constituents were established and were confirmed by DFT calculations. An approach for the design of new porphyrin-like molecules to be carried by liposome is presented.

Synthesis and Liposome Insertion of a New Poly(carboranylalkylthio)porphyrazine to Improve Potentiality in Multiple-Approach Cancer Therapy

ROSA, Angela Maria;RICCIARDI, Giampaolo
2007

Abstract

Liposome insertion of a newly synthesized octa-carboranylhexylthio-porphyrazine (H2HECASPz) with potentiality in anticancer multiple therapy was described at molecular and supramolecular level. Host−guest interactions between H2HECASPz and the liposome constituents were established and were confirmed by DFT calculations. An approach for the design of new porphyrin-like molecules to be carried by liposome is presented.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11563/15229
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