Liposome insertion of a newly synthesized octa-carboranylhexylthio-porphyrazine (H2HECASPz) with potentiality in anticancer multiple therapy was described at molecular and supramolecular level. Host−guest interactions between H2HECASPz and the liposome constituents were established and were confirmed by DFT calculations. An approach for the design of new porphyrin-like molecules to be carried by liposome is presented.
Synthesis and Liposome Insertion of a New Poly(carboranylalkylthio)porphyrazine to Improve Potentiality in Multiple-Approach Cancer Therapy
ROSA, Angela Maria;RICCIARDI, Giampaolo
2007-01-01
Abstract
Liposome insertion of a newly synthesized octa-carboranylhexylthio-porphyrazine (H2HECASPz) with potentiality in anticancer multiple therapy was described at molecular and supramolecular level. Host−guest interactions between H2HECASPz and the liposome constituents were established and were confirmed by DFT calculations. An approach for the design of new porphyrin-like molecules to be carried by liposome is presented.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
