This work deals with the vibrational, thermal and dielectric characterization of a synthetic peptide (S4) released during the proteolysis of human tropoelastin. This peptide was shown to form amyloid-like fibers implied in neurodegenerative pathologies. The comparison between the linear peptides and the associated amyloid-like fibers evidences the strong influence of the secondary structures on the physical structure and chain dynamics of these polypeptides.
Influence of the architecture on the molecular mobility of synthetic fragments inspired from human tropoelastin
BOCHICCHIO, Brigida;PEPE, Antonietta
2015-01-01
Abstract
This work deals with the vibrational, thermal and dielectric characterization of a synthetic peptide (S4) released during the proteolysis of human tropoelastin. This peptide was shown to form amyloid-like fibers implied in neurodegenerative pathologies. The comparison between the linear peptides and the associated amyloid-like fibers evidences the strong influence of the secondary structures on the physical structure and chain dynamics of these polypeptides.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.