MELE, LUIGI
MELE, LUIGI
Dipartimento di Scienze della Salute
A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo article
2018-01-01 Mele, L.; Paino, F.; Papaccio, F.; Regad, T.; Boocock, D.; Stiuso, P.; Lombardi, A.; Liccardo, D.; Aquino, G.; Barbieri, A.; Arra, C.; Coveney, C.; La Noce, M.; Papaccio, G.; Caraglia, M.; Tirino, V.; Desiderio, V.
Antitumoral Activity of the Universal Methyl Donor S-Adenosylmethionine in Glioblastoma Cells
2024-01-01 Mosca, L.; Pagano, C.; Tranchese, R. V.; Grillo, R.; Cadoni, F.; Navarra, G.; Coppola, L.; Pagano, M.; Mele, L.; Cacciapuoti, G.; Laezza, C.; Porcelli, M.
Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress
2022-01-01 Chipurupalli, S.; Ganesan, R.; Martini, G.; Mele, L.; Reggio, A.; Esposito, M.; Kannan, E.; Namasivayam, V.; Grumati, P.; Desiderio, V.; Robinson, N.
Diet-derived ergothioneine induces necroptosis in colorectal cancer cells by activating the SIRT3/MLKL pathway
2022-01-01 D'Onofrio, N.; Martino, E.; Balestrieri, A.; Mele, L.; Cautela, D.; Castaldo, D.; Balestrieri, M. L.
Mi-RNA-888-5p is involved in s-adenosylmethionine antitumor effects in laryngeal squamous cancer cells
2020-01-01 Pagano, M.; Mosca, L.; Vitiello, F.; Ilisso, C. P.; Coppola, A.; Borzacchiello, L.; Mele, L.; Caruso, F. P.; Ceccarelli, M.; Caraglia, M.; Cacciapuoti, G.; Porcelli, M.
Milk Exosomal miR-27b Worsen Endoplasmic Reticulum Stress Mediated Colorectal Cancer Cell Death
2022-01-01 Martino, E.; Balestrieri, A.; Mele, L.; Sardu, C.; Marfella, R.; D'Onofrio, N.; Campanile, G.; Balestrieri, M. L.
MiR-148a-3p Promotes Colorectal Cancer Cell Ferroptosis by Targeting SLC7A11
2023-01-01 Martino, E.; Balestrieri, A.; Aragona, F.; Bifulco, G.; Mele, L.; Campanile, G.; Balestrieri, M. L.; D'Onofrio, N.
MiR-15b-5p and PCSK9 inhibition reduces lipopolysaccharide-induced endothelial dysfunction by targeting SIRT4
2023-01-01 Martino, E.; D'Onofrio, N.; Balestrieri, A.; Mele, L.; Sardu, C.; Marfella, R.; Campanile, G.; Balestrieri, M. L.
MiR-27b attenuates mitochondrial oxidative stress and inflammation in endothelial cells
2023-01-01 D'Onofrio, N.; Prattichizzo, F.; Martino, E.; Anastasio, C.; Mele, L.; La Grotta, R.; Sardu, C.; Ceriello, A.; Marfella, R.; Paolisso, G.; Balestrieri, M. L.
Olive Oil Phenols Prevent Mercury‐Induced Phosphatidylserine Exposure and Morphological Changes in Human Erythrocytes Regardless of Their Different Scavenging Activity
2022-01-01 Notariale, R.; Perrone, P.; Mele, L.; Lettieri, G.; Piscopo, M.; Manna, C.
S-adenosyl-l-methionine overcomes ul3-mediated drug resistance in p53 deleted colon cancer cells
2021-01-01 Mosca, L.; Pagano, M.; Pecoraro, A.; Borzacchiello, L.; Mele, L.; Cacciapuoti, G.; Porcelli, M.; Russo, G.; Russo, A.
S-adenosylmethionine increases the sensitivity of human colorectal cancer cells to 5-fluorouracil by inhibiting P-glycoprotein expression and NF-κB activation
2021-01-01 Mosca, L.; Pagano, M.; Borzacchiello, L.; Mele, L.; Russo, A.; Russo, G.; Cacciapuoti, G.; Porcelli, M.
SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells
2024-01-01 Anastasio, C.; Donisi, I.; Del Vecchio, V.; Colloca, A.; Mele, L.; Sardu, C.; Marfella, R.; Balestrieri, M. L.; D'Onofrio, N.
Sirt3 and metabolic reprogramming mediate the antiproliferative effects of whey in human colon cancer cells
2021-01-01 D'Onofrio, N.; Martino, E.; Balestrieri, A.; Mele, L.; Neglia, G.; Balestrieri, M. L.; Campanile, G.
SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance
2022-01-01 Martino, E.; Balestrieri, A.; Anastasio, C.; Maione, M.; Mele, L.; Cautela, D.; Campanile, G.; Balestrieri, M. L.; D'Onofrio, N.
Synergistic effect of dietary betaines on sirt1-mediated apoptosis in human oral squamous cell carcinoma cal 27
2020-01-01 D'Onofrio, N.; Mele, L.; Martino, E.; Salzano, A.; Restucci, B.; Cautela, D.; Tatullo, M.; Balestrieri, M. L.; Campanile, G.
The role of autophagy in resistance to targeted therapies
2020-01-01 Mele, L.; del Vecchio, V.; Liccardo, D.; Prisco, C.; Schwerdtfeger, M.; Robinson, N.; Desiderio, V.; Tirino, V.; Papaccio, G.; La Noce, M.
Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer
2021-01-01 Vitiello, P. P.; Martini, G.; Mele, L.; Giunta, E. F.; De Falco, V.; Ciardiello, D.; Belli, V.; Cardone, C.; Matrone, N.; Poliero, L.; Tirino, V.; Napolitano, S.; Della Corte, C.; Selvaggi, F.; Papaccio, G.; Troiani, T.; Morgillo, F.; Desiderio, V.; Ciardiello, F.; Martinelli, E.
Whey Improves In Vitro Endothelial Mitochondrial Function and Metabolic Redox Status in Diabetic State
2023-01-01 Martino, E.; Luce, A.; Balestrieri, A.; Mele, L.; Anastasio, C.; D'Onofrio, N.; Balestrieri, M. L.; Campanile, G.
β2-AR blockade potentiates MEK1/2 inhibitor effect on HNSCC by regulating the Nrf2-mediated defense mechanism
2020-01-01 Mele, L.; Del Vecchio, V.; Marampon, F.; Regad, T.; Wagner, S.; Mosca, L.; Bimonte, S.; Giudice, A.; Liccardo, D.; Prisco, C.; Schwerdtfeger, M.; La Noce, M.; Tirino, V.; Caraglia, M.; Papaccio, G.; Desiderio, V.; Barbieri, A.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo article | 1-gen-2018 | Mele, L.; Paino, F.; Papaccio, F.; Regad, T.; Boocock, D.; Stiuso, P.; Lombardi, A.; Liccardo, D.; Aquino, G.; Barbieri, A.; Arra, C.; Coveney, C.; La Noce, M.; Papaccio, G.; Caraglia, M.; Tirino, V.; Desiderio, V. | |
| Antitumoral Activity of the Universal Methyl Donor S-Adenosylmethionine in Glioblastoma Cells | 1-gen-2024 | Mosca, L.; Pagano, C.; Tranchese, R. V.; Grillo, R.; Cadoni, F.; Navarra, G.; Coppola, L.; Pagano, M.; Mele, L.; Cacciapuoti, G.; Laezza, C.; Porcelli, M. | |
| Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress | 1-gen-2022 | Chipurupalli, S.; Ganesan, R.; Martini, G.; Mele, L.; Reggio, A.; Esposito, M.; Kannan, E.; Namasivayam, V.; Grumati, P.; Desiderio, V.; Robinson, N. | |
| Diet-derived ergothioneine induces necroptosis in colorectal cancer cells by activating the SIRT3/MLKL pathway | 1-gen-2022 | D'Onofrio, N.; Martino, E.; Balestrieri, A.; Mele, L.; Cautela, D.; Castaldo, D.; Balestrieri, M. L. | |
| Mi-RNA-888-5p is involved in s-adenosylmethionine antitumor effects in laryngeal squamous cancer cells | 1-gen-2020 | Pagano, M.; Mosca, L.; Vitiello, F.; Ilisso, C. P.; Coppola, A.; Borzacchiello, L.; Mele, L.; Caruso, F. P.; Ceccarelli, M.; Caraglia, M.; Cacciapuoti, G.; Porcelli, M. | |
| Milk Exosomal miR-27b Worsen Endoplasmic Reticulum Stress Mediated Colorectal Cancer Cell Death | 1-gen-2022 | Martino, E.; Balestrieri, A.; Mele, L.; Sardu, C.; Marfella, R.; D'Onofrio, N.; Campanile, G.; Balestrieri, M. L. | |
| MiR-148a-3p Promotes Colorectal Cancer Cell Ferroptosis by Targeting SLC7A11 | 1-gen-2023 | Martino, E.; Balestrieri, A.; Aragona, F.; Bifulco, G.; Mele, L.; Campanile, G.; Balestrieri, M. L.; D'Onofrio, N. | |
| MiR-15b-5p and PCSK9 inhibition reduces lipopolysaccharide-induced endothelial dysfunction by targeting SIRT4 | 1-gen-2023 | Martino, E.; D'Onofrio, N.; Balestrieri, A.; Mele, L.; Sardu, C.; Marfella, R.; Campanile, G.; Balestrieri, M. L. | |
| MiR-27b attenuates mitochondrial oxidative stress and inflammation in endothelial cells | 1-gen-2023 | D'Onofrio, N.; Prattichizzo, F.; Martino, E.; Anastasio, C.; Mele, L.; La Grotta, R.; Sardu, C.; Ceriello, A.; Marfella, R.; Paolisso, G.; Balestrieri, M. L. | |
| Olive Oil Phenols Prevent Mercury‐Induced Phosphatidylserine Exposure and Morphological Changes in Human Erythrocytes Regardless of Their Different Scavenging Activity | 1-gen-2022 | Notariale, R.; Perrone, P.; Mele, L.; Lettieri, G.; Piscopo, M.; Manna, C. | |
| S-adenosyl-l-methionine overcomes ul3-mediated drug resistance in p53 deleted colon cancer cells | 1-gen-2021 | Mosca, L.; Pagano, M.; Pecoraro, A.; Borzacchiello, L.; Mele, L.; Cacciapuoti, G.; Porcelli, M.; Russo, G.; Russo, A. | |
| S-adenosylmethionine increases the sensitivity of human colorectal cancer cells to 5-fluorouracil by inhibiting P-glycoprotein expression and NF-κB activation | 1-gen-2021 | Mosca, L.; Pagano, M.; Borzacchiello, L.; Mele, L.; Russo, A.; Russo, G.; Cacciapuoti, G.; Porcelli, M. | |
| SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells | 1-gen-2024 | Anastasio, C.; Donisi, I.; Del Vecchio, V.; Colloca, A.; Mele, L.; Sardu, C.; Marfella, R.; Balestrieri, M. L.; D'Onofrio, N. | |
| Sirt3 and metabolic reprogramming mediate the antiproliferative effects of whey in human colon cancer cells | 1-gen-2021 | D'Onofrio, N.; Martino, E.; Balestrieri, A.; Mele, L.; Neglia, G.; Balestrieri, M. L.; Campanile, G. | |
| SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance | 1-gen-2022 | Martino, E.; Balestrieri, A.; Anastasio, C.; Maione, M.; Mele, L.; Cautela, D.; Campanile, G.; Balestrieri, M. L.; D'Onofrio, N. | |
| Synergistic effect of dietary betaines on sirt1-mediated apoptosis in human oral squamous cell carcinoma cal 27 | 1-gen-2020 | D'Onofrio, N.; Mele, L.; Martino, E.; Salzano, A.; Restucci, B.; Cautela, D.; Tatullo, M.; Balestrieri, M. L.; Campanile, G. | |
| The role of autophagy in resistance to targeted therapies | 1-gen-2020 | Mele, L.; del Vecchio, V.; Liccardo, D.; Prisco, C.; Schwerdtfeger, M.; Robinson, N.; Desiderio, V.; Tirino, V.; Papaccio, G.; La Noce, M. | |
| Vulnerability to low-dose combination of irinotecan and niraparib in ATM-mutated colorectal cancer | 1-gen-2021 | Vitiello, P. P.; Martini, G.; Mele, L.; Giunta, E. F.; De Falco, V.; Ciardiello, D.; Belli, V.; Cardone, C.; Matrone, N.; Poliero, L.; Tirino, V.; Napolitano, S.; Della Corte, C.; Selvaggi, F.; Papaccio, G.; Troiani, T.; Morgillo, F.; Desiderio, V.; Ciardiello, F.; Martinelli, E. | |
| Whey Improves In Vitro Endothelial Mitochondrial Function and Metabolic Redox Status in Diabetic State | 1-gen-2023 | Martino, E.; Luce, A.; Balestrieri, A.; Mele, L.; Anastasio, C.; D'Onofrio, N.; Balestrieri, M. L.; Campanile, G. | |
| β2-AR blockade potentiates MEK1/2 inhibitor effect on HNSCC by regulating the Nrf2-mediated defense mechanism | 1-gen-2020 | Mele, L.; Del Vecchio, V.; Marampon, F.; Regad, T.; Wagner, S.; Mosca, L.; Bimonte, S.; Giudice, A.; Liccardo, D.; Prisco, C.; Schwerdtfeger, M.; La Noce, M.; Tirino, V.; Caraglia, M.; Papaccio, G.; Desiderio, V.; Barbieri, A. |