Eight new oleanane saponins (1-8) together with four know saponins (9-12) were isolated from the aerial parts of Meryta denhamii. Their structures were elucidated by ID and 2D NMR experiments including ID TOCSY, DQF-COSY, ROESY, HSQC, and HMBC spectroscopy, as well as ESIMS analysis. The antiproliferative activity of all compounds was evaluated using three murine and human cancer cell lines: J774.A1, HEK-293, and WEHI-164.
Antiproliferative Oleanane Saponins from Meryta denhamii.
VASSALLO, ANTONIO;
2008-01-01
Abstract
Eight new oleanane saponins (1-8) together with four know saponins (9-12) were isolated from the aerial parts of Meryta denhamii. Their structures were elucidated by ID and 2D NMR experiments including ID TOCSY, DQF-COSY, ROESY, HSQC, and HMBC spectroscopy, as well as ESIMS analysis. The antiproliferative activity of all compounds was evaluated using three murine and human cancer cell lines: J774.A1, HEK-293, and WEHI-164.File in questo prodotto:
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Cioffi at al. - Journal of Natural Products 2008.pdf
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