Absolute configurations (+)-(4S), (+)-(3S,4R), (-)-(2S,4S), and (-)-(1R,2R,4S) were assigned, for the first time, to bioactive furanogermacranes extracted from Commiphora erythraea resin by DFT computational analysis of their ORD curves and ECD spectra. This analysis established that all of these compounds share the same absolute configuration at the methyl-substituted carbon thus allowing us to hypothesize a biosynthetic relationship among these structurally related metabolites.
Absolute configuration of bioactive furanogermacrenones from Commiphora erythraea (Ehrenb) Engl. by computational analysis of their chiroptical properties
SANTORO, ERNESTO;SUPERCHI, Stefano
2014-01-01
Abstract
Absolute configurations (+)-(4S), (+)-(3S,4R), (-)-(2S,4S), and (-)-(1R,2R,4S) were assigned, for the first time, to bioactive furanogermacranes extracted from Commiphora erythraea resin by DFT computational analysis of their ORD curves and ECD spectra. This analysis established that all of these compounds share the same absolute configuration at the methyl-substituted carbon thus allowing us to hypothesize a biosynthetic relationship among these structurally related metabolites.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Tetrahed_2014_8033.pdf
solo utenti autorizzati
Descrizione: pdf finale
Tipologia:
Pdf editoriale
Licenza:
DRM non definito
Dimensione
1.57 MB
Formato
Adobe PDF
|
1.57 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
